CHANTIX is a non-nicotine pill.

CHANTIX is a non-nicotine prescription medicine specifically developed to help adults 18 and over quit smoking. Over 6 million people in the U.S. have already been prescribed CHANTIX.*

How is CHANTIX different from other smoking cessation products?

CHANTIX does not contain nicotine. It works in two ways. It targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them. It is believed that CHANTIX also activates these receptors, causing a reduced release of dopamine compared to nicotine.

It’s recommended that you begin your CHANTIX treatment a week before you stop smoking completely. This gives CHANTIX a chance to build up in your body. You may smoke during the first week of your CHANTIX treatment, but you should stop smoking completely on Day 8 of your treatment.

CHANTIX is proven to work.

Studies show: At the end of 12 weeks of CHANTIX, 44% of patients were able to quit smoking versus 18% on the sugar pill. It also helped reduce the urge to smoke.

CHANTIX has been proven to be more effective in helping smokers quit than Zyban® (bupropion hydrochloride). The average person in these studies had been a smoker for more than 24 years. The trials involved a mix of men and women who smoked an average of 10 or more cigarettes a day.

Learn about the study.

1,022 patients were enrolled in this study, and results were duplicated in another identically designed clinical trial.

Patients received either CHANTIX 1 mg twice a day, Zyban 150 mg twice a day, or sugar pills twice a day for 12 weeks. In addition to the pills, patients were also given a booklet on quitting smoking and also received brief counseling at each visit.

In weeks 9 through 12 in the study, the smoking status of each patient was checked, and the information was compared among the 3 groups. Patients were considered quit if they did not smoke a cigarette (not even a puff) or use other nicotine products for the final 4 weeks of treatment. CHANTIX was proven to be more effective than the sugar pills or Zyban®.

The 12-week quitting plan just for CHANTIX users.

CHANTIX is proven to be effective, but even with treatment, quitting can be tough. For many people, quitting smoking can be both a physical and a behavioral challenge. That’s why we also offer the GETQUIT™ Support Plan at no extra cost.

Created just for people who take CHANTIX, GETQUIT is a 12-week quitting plan designed to help protect you against slipping up. It provides just-in-time support, real-life strategies, and live smoking cessation experts who can talk you through moments when you may be tempted to smoke.

How does CHANTIX work?

CHANTIX contains no nicotine. You may wonder how a non-nicotine pill could help you quit smoking. Well, first, you have to know how nicotine works.

There are receptors for nicotine in your brain. When you smoke, the nicotine you inhale attaches to these receptors. This sends a message to a different part of your brain to release a chemical called dopamine. Dopamine gives you a feeling of pleasure. But it does not last long. That’s why your body craves more nicotine. This can become a vicious cycle.

CHANTIX is different from most other quit-smoking products. It targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them. By activating these nicotine receptors, it is also believed that CHANTIX causes less dopamine — compared to nicotine — to be released.

Side Effects and Important Safety Information

What is the most important safety information about CHANTIX?

Some patients have had changes in behavior, agitation, depressed mood, and suicidal thoughts or actions while using CHANTIX to help them quit smoking. Some people had these symptoms when they began taking CHANTIX, and others developed them after several weeks of treatment or after stopping CHANTIX. If either you, your family or caregiver notice agitation, depressed mood, or changes in behavior that are not typical for you, or if you develop suicidal thoughts or actions, stop taking CHANTIX and call your doctor right away. Also tell your doctor about any history of depression or other mental health problems before taking CHANTIX, as these symptoms may worsen while taking CHANTIX.

Is there other important safety information?

Use caution driving or operating machinery until you know how quitting smoking and/or using CHANTIX may affect you.

You should not use CHANTIX while using other treatments to quit smoking. Tell your doctor if you use other treatments to quit smoking.

What are the most common side effects?

The most common side effects of CHANTIX include:

* nausea (30%)
* sleep problems (trouble sleeping, or vivid, unusual, or strange dreams)
* constipation
* gas
* vomiting

These are not all the side effects of CHANTIX. Ask your doctor or pharmacist for more information.

What should I tell my doctor before starting CHANTIX?

Tell your doctor about all your medical conditions, including if you:

* have ever had depression or other mental health problems, as these symptoms may worsen while taking CHANTIX.
* experienced nicotine withdrawal symptoms with prior quit attempts, with or without CHANTIX. Quitting smoking, with or without CHANTIX, can result in nicotine withdrawal symptoms (such as depressed mood, agitation) or a worsening of existing mental health problems, such as depression.
* have kidney problems or get kidney dialysis. Your doctor may prescribe a lower dose of CHANTIX for you.
* are pregnant or plan to become pregnant. CHANTIX has not been studied in pregnant women. It is not known if CHANTIX will harm your unborn baby. It is best to stop smoking before you get pregnant.
* are breastfeeding. Although it was not studied, CHANTIX may pass into breast milk. You and your doctor should discuss alternative ways to feed your baby if you take CHANTIX.

Tell your doctor about all your other medicines, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially, tell your doctor if you take:

* insulin
* asthma medicines
* blood thinners

When you stop smoking, there may be a change in how these and other medicines work for you.

Know the medicines you take. Keep a list of them with you to show your doctor and pharmacist.

A 12-Week Prescription:

* CHANTIX should be taken after eating and with a full glass (8 ounces) of water.
* A 12-week CHANTIX prescription includes 1 Starting Month PAK and 2 Continuing Month PAKS.
* Within each one-month PAK are 4 Weekly doses of CHANTIX.

The first week:

* In the first week of CHANTIX, white pills are taken.
* During days 1-3, take 1 white pill every day.
* During days 4-7, take 2 white pills every day. One in the morning and one in the evening.

The remaining weeks:

* During weeks 2-12, take 2 blue pills every day. One in the morning and one in the evening.
* Remember, you should always take CHANTIX as prescribed by your doctor.

Important Tips

Here are some important things to remember when taking CHANTIX:

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Choose a Quit Date. Your Quit Date is the day you stop smoking completely. It should be on your 8th day of taking CHANTIX.
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Start taking CHANTIX one week before your Quit Date. This allows CHANTIX time to build up in your body.
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You may smoke during your first week on CHANTIX, but you should stop smoking completely on your Quit Date - day 8 of your treatment.
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CHANTIX should be taken after eating and with a full glass (8 ounces) of water.
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If you miss a dose, take it as soon as you remember. If it’s close to the time of your next dose, wait. Then just take your next regular dose.
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If you slip up and smoke while taking CHANTIX, don’t give up. Keep trying to quit and keep taking CHANTIX. Some people need a few weeks for it to work best. In studies, some people who smoked after their Quit Date were able to quit successfully.
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The urge to smoke and withdrawal symptoms may be strongest in the first few weeks after you quit smoking. CHANTIX can help reduce the urge to smoke, so keep taking it as prescribed. And try to avoid situations that may tempt you to smoke during your first weeks of quitting.
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Some patients have reported changes in behavior, agitation, depressed mood, suicidal thoughts or actions when attempting to quit smoking while taking CHANTIX or after stopping CHANTIX. If either you, your family, or caregiver notice agitation, depressed mood, or changes in behavior that are not typical for you, or if you develop suicidal thoughts or actions, stop taking CHANTIX and call your doctor right away. Also tell your doctor about any history of depression or other mental health problems before taking CHANTIX, as these symptoms may worsen while taking CHANTIX.
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When you try to quit smoking, with or without CHANTIX, you may have symptoms that may be due to nicotine withdrawal, including urge to smoke, depressed mood, trouble sleeping, irritability, frustration, anger, feeling anxious, difficulty concentrating, restlessness, decreased heart rate, and increased appetite or weight gain.
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For many people, quitting smoking is both a physical and a behavioral challenge, even with treatment. That’s why your prescription comes with GETQUIT™ - a support plan designed to help protect you against slipping up. To learn more about GETQUIT and how to enroll, visit the GETQUIT Support Plan section. To receive all the benefits of GETQUIT, it’s recommended that you enroll at least one week before your Quit Date.

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